Q:

In red blood cells, carbonic anhydrase catalyses the formation of carbonic acid which then disassociates into bicarbonate ions and hydrogen ions. What happens next?

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In red blood cells, carbonic anhydrase catalyses the formation of carbonic acid which then disassociates into bicarbonate ions and hydrogen ions. What happens next?


  1. bicarbonate ions bind to haemoglobin
  2. hydrogen ions move into the plasma to be buffered by bicarbonate ions
  3. hydrogen ions are buffered by haemoglobin
  4. chloride ions enter the rbc to form hydrochloric acid (HCl)

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C: Haemoglobin is a protein so can act as a buffer, thus removing the hydrogen ions from solution. The bicarbonate ions move out of the rbc into the plasma in exchange for chloride ions. 

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