Q:

A plaque in a coronary vessel wall will result in a decrease in the lumen diameter of a coronary artery and in less oxygen being delivered to the heart muscle. Why is this?

waelhammad
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2022-10-18
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A plaque in a coronary vessel wall will result in a decrease in the lumen diameter of a coronary artery and in less oxygen being delivered to the heart muscle. Why is this?

  1. A protruding plaque increases the distance blood needs to travel and this increases resistance to flow.
  2. A narrow artery restricts blood flow by increasing blood’s viscosity.
  3. The constricted artery causes the pressure gradient to decrease which results in lower blood flow.
  4. The decrease in artery radius will cause blood volume flow rate to decrease.
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waelhammad
2022-10-18
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D: Poiseuille’s law states that volume flow rate is proportional to radius the 4th power so a decrease in radius results in a decrease in flow rate and hence less oxygen being delivered to the myocardium.

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