Q:

Which of the following mechanisms operates in the nephron to maintain pH balance in the body

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Which of the following mechanisms operates in the nephron to maintain pH balance in the body? 


  1. Bicarbonate ions from the tubule cells are secreted into the fi ltrate, then H + + HCO 3 − → H 2 CO 3 → CO 2 + H 2 O
  2. . In tubule cells CO 2 + H 2 O → H 2 CO 3 → H + + HCO 3 − then hydrogen ions are secreted into the fi ltrate
  3. . In tubule cells CO 2 + H 2 O → H 2 CO 3 → H + + HCO 3 − then hydrogen ions are transported into the peritubular capillaries
  4. In tubule cells CO 2 + H 2 O → H 2 CO 3 → H + + HCO 3 − then bicarbonate ions are secreted into the fi ltrate

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B: Carbon dioxide and water form hydronium and bicarbonate ions, the hydronium ions being secreted into the fi ltrate for excretion in urine. 

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