Q:

The diagnosis of chronic granulomatous disease CGD is MOST often made by

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The diagnosis of chronic granulomatous disease CGD is MOST often made by


  1. DNA analysis
  2. flow cytometry
  3. neutrophil GGPD assay
  4. erythrocyte GGPD assay
  5. nitroblue tetrazolium dye test

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(B). The diagnosis is most often made by performing flow cytometh using  dihydrorhodamine 123 (DHR) to measure oxidant production through its increased fluorescence when oxidized by H202.

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