A 3-year-old boy presented with recurrent subcutaneous abscesses, Iymphadenitis, osteomyelitis, and family history of recurrent infections

(D). Granuloma formation and inflammatory processes are a hallmark of chronic granulomatous disease CGD and may be the presenting symptoms that prompt testing for CGD if they cause pyloric outlet obstruction, bladder outlet or ureter obstruction, or rectal fistulas and granulomatous colitis simulating Crohn disease.