Q:

A 15-year-old boy presented with high fever, lymphadenopathy, hepatosplenomegaly, recurrent skin infections, silvery hair, andphotophobia. Lastyear, he developed ataxia

safaTerkawi
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2022-09-20
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A 15-year-old boy presented with high fever, lymphadenopathy, hepatosplenomegaly, recurrent skin infections, silvery hair,andphotophobia. Lastyear, he developed ataxia

TheMOSTcharacteristicfindinginthisconditionis

  1. neutropenia
  2. thrombocytopenia
  3. prolonged bleeding time
  4. prolonged prothrombine time
  5. prolonged partial prothrombine time
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safaTerkawi
2022-09-20
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(C). Patients with Chédiak-Higashi syndrome (CHS) have prolonged bleeding times with normal platelet counts, resulting from impaired platelet aggregation associated with a deficiency of the dense granules containing adenosine diphosphate and serotonin. 

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