A 9-year-old boy with acute lymphoblastic leukemiaon chemotherapy, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophiI count (ANC)was 450/ uL and hemoglobin level was 10gm/dl

(D). A decline in the WBC c0unt typically occurs 7-10 days after administration of the anticancer drug and may persist for 1-2 wk. Patients with chemotherapy/ radiation~ related neutropenia and fever must be treated aggressively with broad~spectrum antibiotics.