Q:

The earliest clinical feature of ataxia-telangiectasia is

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 The earliest clinical feature of ataxia-telangiectasia is  


  1. ataxia
  2. jaundice
  3. inability to walk
  4. ocular telangiectasias
  5. cutaneous telangiectasias

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(A). Ataxia typically becomes evident soon after these children begin to walk and progresses until they are confined to a wheelchair, usually by the age of 10-12 yr. The telangiectasias begin to develop at 3-6 yr of age

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