One of the following is FAISE in hemolytic disease of the newborn caused by blood group A and B incompatibility

(D). Although antibodies against A and B factors occur without previous immunization ("natural" antibodies), they are usually lgM antibodies that do not cross the placenta. However, lgG antibodies to A antigen may be present and these do cross the placenta, so A-O isoimmune hemolytic disease may be found in first-born infants.