Q:

When in solution, an acidic drug also exists as its salt. What feature does the salt of a drug have that may not be shared by the acid form of the drug

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When in solution, an acidic drug also exists as its salt. What feature does the

salt of a drug have that may not be shared by the acid form of the drug?


  1. The salt of the drug does not carry an electrical charge but the acid form does.
  2. The salt of the drug may be more soluble in lipid than the acid form of the drug
  3. The acid form of the drug is ionised whereas the salt is not.
  4. The salt of the drug may be more soluble in water than the acid form of the drug.

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D: The salt of the drug, being ionised, is more soluble in water (a

polar liquid) than is the drug molecule.

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