Q:

A 28-day-old boy presented with prolonged neonatal jaundice, lethargy, poor feeding,and failure to regainbirth weight

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A 28-day-old boy presented with prolonged neonatal jaundice, lethargy, poor feeding,and failure to regainbirth weight. On examination there are hepatomegaly and cataract. Of the following, the MOST likely injured organs in this disease are


  1. eyes, liver, and brain
  2. kidney, liver, and eyes
  3. kidney, liver, and brain
  4. kidney, heart , and brain
  5. pancreas, liver, and brain

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(C). ln galactosemia, without the transferase enzyme, the infant is unable to metabolize galactose-1-phosphate, the accumulation of which results in injury to kidney, liver, and brain. 

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