Q:

The mainstay of treatment of phenylketonurea (PKU) is especial diet. All the following statements are true EXCEPT

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The mainstay of treatment of phenylketonurea (PKU) is especial diet. All the following statements are true EXCEPT


  1. phenylalanine not totally restricted
  2. all patients kept on a phenylalanine-restricted diet lifelong
  3. especial diet should be used before and during pregnancy in mother with PKU
  4. especial diet should be started when blood phenylalanine levels above 10 mg/dL
  5. especial diet is not advocated in mild hyperphenylalaninemia whose levels are >6 mg/Dl

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(E). The mainstay of treatment of PKU is a low-phenylalanine diet. Most physicians advocate phenylalanine-restricted diet'in patients with mild hyperphenylalaninemia whose levels are persistently above >6 mg/ dL (360 umole/L). It is generally accepted that infants with persistent (more than a few days) plasma levels of phenylalanine 26 mg/dL (360 umole/L) should be treated with a phenylalanine-restricted diet similar to that for classic PKU

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