Q:

A 5-year-old asymptomatic male child with strong positive family history of Huntington chorea,

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A 5-year-old asymptomatic male child with strong positive family history of Huntington chorea, mother is highly concern about her child possible genetic affection, she asked for predictive genetic testing. Of the following, the MOST appropriate explanation is that


  1. whatever the result it will not affect the disease process
  2. this is an age dependent type of genetic disorder and may not manifest ever
  3. leave the decision to the child when he is grown up
  4. it may lead to discrimination
  5. we should weigh the benefits VS risks of testing

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(C). In fact, all the mentioned explanations about the disease are true but it is generally agreed that predictive genetic tests should be performed for children if the results of the test will benefit the medical management of the child. Otherwise, the test should be deferred until the child has an understanding of the risks and benefits of testing and can provide informed consent.

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