Q:

Digoxin has a very narrow therapeutic index

Anwaar
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2022-09-10
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Digoxin has a very narrow therapeutic index, the rapeutic plasma digoxin concentrations are 0.5-2.0 ng/mL; a level>2 ng/mL is considered toxic and a level>6 ng/mL is considered potentially fatal. All the following medications increase serum digoxin concentration EXCEPT

  1. tetracyclin
  2. amiodarone
  3. itraconazole
  4. clarithromycin
  5. spironolactone
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Anwaar
2022-09-10
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(E). Sodium bicarbonate is antidote for tricyclic antidepressants

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