Q:

Clinical manifestations of organophosphate toxicity relate to the accumulation of acetylcholine at peripheral nicotinic and muscarinic synapses and in the CNs

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Clinical manifestations of organophosphate toxicity relate to the accumulation of acetylcholine at peripheral nicotinic and muscarinic synapses and in the CNs, All the following are symptoms of cholinergic excessat muscarinic receptors EXCEPT


  1. miosis
  2. emesis
  3. salivation
  4. bradycardia
  5. urine etention

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(E).A commonly used mnemonic for the symptoms of cholinergic excess at muscarinic receptors is DUMBBELS,which stands for diarrhea/defecation, urination, miosis,bronchorrhea/bronchospasm, bradycardia,emesis,lacrimation,andsalivation.

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