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Carbon monoxide (CO) is a colorless, odorless gas produced during the combustion of any carbon-containing fuel (the less efficienthe combustion

Anwaar
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2022-09-10
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Carbon monoxide (CO) is a colorless, odorless gas produced during  the combustion of any carbon-containing fuel (the less efficienthe combustion, the greater the amount of C0 produced). All the following are true about CO poisoning EXCEPT

  1. CO displaces nitric oxide (NO)from proteins
  2. NO is responsible for headache, syncope, and hypotension
  3. HbCO levels are well correlated with clinical signs of toxicity
  4. CO bind to cytochrome oxidase, disrupt cellular respiration
  5. CO binds to hemoglobin with an affinity >200 times that of oxygen
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Anwaar
2022-09-10
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(C).CO displaces oxygen and creates a conformational change in hemoglobin that impairs the delivery of oxygen to the tissues,leading to tissue hypoxia. HbCO levels are not well correlatedwith clinicalsigns of toxicity, likely because CO interacts with multiple proteins in addition to hemoglobin

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