Q:

The King's College criteria for consideration of liver transplantation in acetaminophen poisoning with acute liver failure (stage 3) include all the following EXCEPT

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The King's College criteria for consideration of liver transplantation in acetaminophen poisoning with acute liver failure (stage 3) include all the following EXCEPT


  1. coagulopathy (INR >6)
  2. acidemia (serum pH <7.3)
  3. serum lactic acid >3 mmol/L
  4. grade ill or IV hepatic encephalopathy
  5. renal dysfunction (creatinine >3.4 mg/dL)

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(C). A serum lactic acid >3 mmol/L (after IV fluids) adds to both the sensitivity and specificity of the criteria to predict death without liver transplant. The degree of transaminase elevation is not a factor in this decision making process

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