Q:

The observation of significantly increasing number of imprinting disorders as Beckwith-Wiedemann and Angelman syndrome are MOST likely due to

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The observation of significantly increasing number of imprinting disorders as Beckwith-Wiedemann and Angelman syndrome are MOST likely due to


  1. new methodsof prenatal diagnosis (amniocentesis)
  2. new technology of gene therapy
  3. assisted reproductive technology
  4. increase radiation exposure
  5. high pressure electricity chainsin large cities

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(C). Several studies suggest that there may be a small but significantly increased incidence of imprinting disorders, specifically Beckwith-Wiedemann and Angelman syndrome, associated with assisted reproductive technologies such as in vitro fertilization and intracytoplasmic sperm injection. However, the overall incidence of these disorders in children conceived using assisted reproductive technologies is likely to be <1%.

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