The recurrence risk of multifactorial inheritance are characterized by all the following EXCEPT

(C). Some multifactorial inherited disorders have a sex predilection, as indicated by an unequal male: female incidence. Pyloric stenosis, for example, is more common in males, whereas congenital dislocation of the hips is more common in females. Where there is an altered sex ratio, the risk is higher for the relatives of an index case whose gender is less commonly affected than relatives of an index case of the more commonly affected gender. For example, the risk to the son of an affected female with infantile pyloric stenosis is 18%, compared with the 5% risk for the son of an affected male. An affected female presumably has a greater genetic susceptibility, which she can then pass on to her offspring