The MOST important reason for chromosomal analysis in persons suspected of having Down syndrome is to
belongs to book: MCQs in Pediatrics Review of Nelson Textbook of Pediatrics|Zuhair M Almusawi, Hasanein Ghali|20th edition| Chapter number:10| Question number:10.33
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(D). Chromosome analysis is indicated in every person suspected of having Down syndrome. If a translocation is identified, parental chromosome studies must be performed to determine whether one of the parents is a translocation carrier, which carries a high recurrence risk for having another affected child
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