Q:

In a patient with a red cell count (RCC) of 4 x 1012/litre, a haemoglobin (Hb) of 7.5 g/100 ml and a haematocrit of 0.28:

safaTerkawi
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2022-08-20
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In a patient with a red cell count (RCC) of 4 x 1012/litre, a haemoglobin (Hb) of 7.5 g/100 ml and a haematocrit of 0.28:

 

  1. The mean corpuscular haemoglobin (MCH) is nearer 20 picograms (pg) than 20 nano-grams (ng). 1pg=10-12 g; 1 ng=10-9 g.
  2. The mean cell volume (MCV) is nearer 95 than 70 fl (1 femtolitre=1 um3 ).
  3. The mean corpuscular haemoglobin concentration (MCHC) is nearer 30 than 35 g/100 ml.
  4. The cause of the anaemia is most likely to be vitamin B12 deficiency.
  5. The patient requires a blood transfusion.
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safaTerkawi
2022-08-20
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a. True Hb/litre 75g MCH18.751012 g18.75 pg RCC/litre 41012 This is below normal (27–32 pg).

b. False Red cell volume/litre 0.28 MCV litres70 fl. Red cell count/litre 41012 Since the normal volume is about 75–95 fl, these cells are microcytic.

c. True Hb 7.5 MCHC 26.8 g/100 ml Haematocrit 0.28

Since the normal MCHV is about 30–35 g/100 ml, these cells are hypochromic.

d. False This microcytic, hypochromic picture is characteristic of iron deficiency.

e. False Moderate iron deficiency anaemia of this sort responds well to iron therapy: blood transfusions should not be used unless absolutely necessary

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