For each of the releasing or inhibiting hormones A–E, select the best option from the follow-ing list of effects

A. Option 2 An effect on adrenal cortical activity. CRH from the hypothalamus stimulates the anterior pituitary gland to produce ACTH.

B. Option 1 An effect on somatomedin levels in the blood. GRH stimulates the anterior pituitary gland to secrete GH (growth hormone), which in turn promotes somatomedin synthesis in the liver.

C. Option 3 An effect on lactation. PIH is involved in prolactin secretion from the anterior pituitary gland. Reduction of PIH secretion seems to be the main factor in controlling prolactin secretion. Prolactin stimulates milk formation in the breasts.

D. Option 5 An effect on TSH secretion. TRH (thyrotropin-releasing hormone) stimulates the anterior pituitary gland to secrete TSH (thyroid-stimulating hormone) that in turn increases activity in the thyroid gland.

E. Option 4 An effect on spermatogenesis. LHRH (luteinizing hormone-releasing hormone) stimulates the anterior pituitary gland to secrete LH (luteinizing hormone) that in the male promotes spermatogenesis