Q:

Adrenocorticotrophic hormone (ACTH) secretion increases

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Adrenocorticotrophic hormone (ACTH) secretion increases.


  1. When the median eminence of the hypothalamic is stimulated.
  2. When aldosterone blood level falls.
  3. When cortisol blood levels fall.
  4. In bursts during the night as the normal hour of wakening approaches.
  5. Following severe trauma.

All Answers

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A. True The median eminence secretes corticotropin-releasing hormone (CRH), the releasing hormone for ACTH.

B. False Aldosterone secretion is regulated mainly by the renin/angiotensin system.

C. True This negative feedback helps to maintain the blood cortisol level.

D. True This is part of the circadian rhythm which produces high morning cortisol levels.

E. True Most forms of stress increase ACTH output by their neural input to the median eminence of the hypothalamus where CRH is formed.

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