Q:

A drug which inhibits carbonic anhydrase decreases

safaTerkawi
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2022-08-11
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 A drug which inhibits carbonic anhydrase decreases.

  1. Bicarbonate formation and reabsorption in the kidney.
  2. Plasma bicarbonate levels.
  3. Blood pH
  4. Urinary loss of potassium ions.
  5. Urinary volume and pH.
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safaTerkawi
2022-08-11
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A. True Carbonic anhydrase in tubular cells catalyses the combination of CO2 and H2O to form H2CO3 which ionizes into H and HCO3 ions.

B. True This is determined mainly by renal bicarbonate formation.

C. True This falls as the plasma bicarbonate level falls.

D. False More K is secreted by the tubules in exchange for sodium since there are fewer H ions to compete with K in the sodium/potassium exchange pump.

E. False Failure to reabsorb HCO3 results in an osmotic diuresis of alkaline urine.

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