Q:

The renal clearance of a substance

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 The renal clearance of a substance.


  1. Is inversely related to its urinary concentration, U.
  2. Is directly related to the rate of urine formation, V.
  3. Is directly related to its plasma concentration, P.
  4. Is expressed in units of volume per unit time.
  5. Must fall in the presence of metabolic poisons.

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A. False It is directly related to urinary concentration.

B. True Clearance tends to fall at low urinary flow rates.

C. False It is inversely related to plasma concentration.

D. True Clearance=UV/P in units of volume/unit time.

E. False It rises if the substance is normally reabsorbed by an active process

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