Q:

Lower motor neurone disease

safaTerkawi
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2022-08-10
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 Lower motor neurone disease.

  1. Causes loss of voluntary movements but not of reflex movements.
  2. Is a later stage of upper motor neurone disease.
  3. Causes eventual wasting of the muscles concerned.
  4. Does not affect ventilation of the lungs.
  5. Is associated with involuntary twitchings of small fasciculi in the affected muscles.
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safaTerkawi
2022-08-10
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A. False The muscles are paralysed and not capable of voluntary or reflex movements.

B. False It is totally independent of upper motor neurone disease.

C. True It leads to ‘disuse atrophy’.

D. False Ventilation will be affected if the phrenic and intercostal nerves are involved.

E. True ‘Fasciculation’ is due to denervation hypersensitivity; muscles become ultra-sensitive to small amounts of acetylcholine released from the degenerating nerve terminals.

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