Acetylcholine

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2022-08-10

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Acetylcholine.

Acts on the same type of receptor on postganglionic fibres in sympathetic and parasym-pathetic ganglia.
Acts on the same type of receptor on target organs at cholinergic sympathetic and para-sympathetic nerve terminals.
Acts on the same type of receptor at autonomic ganglia and at somatic neuromuscular junctions.
Acts as an excitatory transmitter in the basal ganglia.
In blood is hydrolyzed by the same cholinesterase as is found at neuromuscular junc-tions.

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safaTerkawi

2022-08-10

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A. True These are ‘nicotinic’ receptors and the action is blocked at both sites by drugs such as hexamethonium.

B. True These are ‘muscarinic’ receptors and the action is blocked at both sites by atropine.

C. False The receptors are different; curare blocks transmission at somatic neuromuscular junctions but not at ganglia.

D. True Anticholinergic drugs are sometimes useful in the treatment of muscle rigidity in Parkinsonism.

E. False The ‘pseudocholinesterase’ found in blood differs from the ‘true cholinesterase’ found near neuromuscular junction

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