Q:

The blood–brain barrier

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The blood–brain barrier.


  1. Slows equilibration of solutes between blood and brain tissue fluids.
  2. Is a more effective barrier for fat-soluble substances than water-soluble substances.
  3. Is a more effective barrier in infants than in adults.
  4. Is a more effective barrier for CO2 than for O2.
  5. Permits hydrogen ions to pass freely.

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 A. True Capillary permeability is lower in the brain than in other tissues.

B. False Fat-soluble substances cross readily due to the lipid in cell membranes.

C. False The reverse is true; bilirubin, which cannot pass in the adult, does so in infants.

D. False Both CO2 and O2 cross the blood–brain barrier easily.

E. False This protects brain tissues against sudden changes in the pH of blood.

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