Q:

As blood passes through systemic capillaries

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As blood passes through systemic capillaries.


  1. pH rises.
  2. HCO3 ions pass from red cells to plasma.
  3. Cl ion concentration in red cells falls.
  4. Its oxygen dissociation curve shifts to the right.
  5. Its ability to deliver oxygen to the tissues is enhanced.

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 A. False It falls, due largely to CO2 uptake.

B. True  Incoming CO2 is converted to HCO3 - (carbonic anhydrase in RBCs catalyses the reaction CO2+H2O=H++CO3 -; HCO3 - migrates out as its concentration rises.

C. False  It rises as Cl moves in to replace departing HCO3- in the ‘chloride shift’.

D. True Due largely to the rise in blood PCO2.

E. True Due to the shift of the oxygen dissociation curve.

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