Red cell formation is increased

 A. False  Healthy normal people do not benefit from vitamin B12 supplements.

B. True  The RBC deficit is corrected by bone marrow stimulation by erythropoietin.

C. True  The reduced oxygen carrying capacity of the blood causes release of erythropoietin which stimulates RBC stem cells in the bone marrow.

D. True  The anaemia seen in nephrectomized patients is due largely to lack of erythropoietin.

E. True  A raised reticulocyte count is evidence of a hyperactive bone marrow.