Q:

Excessive tissue fluid (oedema) in the legs may

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Excessive tissue fluid (oedema) in the legs may


  1. Be associated with a raised extracellular fluid volume.
  2. Result from hepatic disease.
  3. Result from blockage of pelvic lymphatics
  4. Increase local interstitial fluid pressure.
  5. Result from a high arterial blood pressure in the absence of heart failure.

All Answers

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A. True   Oedema is an increase in the interstitial component of ECF.

B. True   Albumin deficiency reduces plasma colloid osmotic pressure.

C. True   Protein accumulates in interstitial fluid and reduces the colloid osmotic pressure gradient across the capillary wall.

D. True   This contributes to a new pressure equilibrium.

E. False   Arteriolar constriction in hypertension raises arterial, but not capillary, pressure.

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