Q:

Antibodies (agglutinins) of the A and B red cell antigens (agglutinogens)

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 Antibodies (agglutinins) of the A and B red cell antigens (agglutinogens)


  1. Are present in fetal plasma.
  2. Cause haemolysis of RBCs containing the A and B antigens when added to a suspension of red cells in saline
  3. Do not normally cross the placental barrier.
  4. Have a molecular weight in excess of 500 000
  5. Are monovalent

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A. False  They form shortly after birth, possibly in response to A and B antigens carried into the body by invading bacteria.

B. False  They cause agglutination (clumping) of A, B and AB cells.

C. True  Unlike Rh antibodies which have a smaller molecular size.

D. True  Around 1000000.

E. False  They are divalent and hence cause red cells to adhere to one another during agglutination.

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